I was struggling with this and saw some old posts in the forums here but none appeared to work for BP >  1.5. The problem remove the Setting > General tab from the users profile settings and wp_admin_bar (we have single sign-on and this would have screwed it. The code
function alt_bp_change_settings_default() {
	global $bp;
	// switch the settings default to notifications 
	$args = array(  'parent_slug' => 'settings',
			'screen_function' => 'bp_core_screen_notification_settings',
			'subnav_slug' => 'notifications'
			);
	bp_core_new_nav_default( $args );
	// remove settings > general from wp_admin_bar
	if ( bp_use_wp_admin_bar() ) {
		add_action( 'wp_before_admin_bar_render', create_function(
		'', 'global $wp_admin_bar; $wp_admin_bar->remove_menu( "my-account-settings-general" );' ) );
	}
}
add_action( 'bp_setup_nav','alt_bp_change_settings_default', 5);
function alt_bp_remove_general() {
	global $bp;
	bp_core_remove_subnav_item( $bp->settings->slug, 'general' );
}
add_action( 'bp_setup_nav', 'alt_bp_remove_general', 200);