I just tried the work-around (hack) provided by @puckettventures and it does solve the issue. However, this is not ideal because those changes will be lost on update.
I’m experiencing the same issue. After I visit BuddyPress pages and then navigate to any standard or template page, except the homepage, but including the blog, I get a 404. Sometimes a simple refresh will work. Sometimes navigating to a new page will work. Sometimes the issue will not be fixed unless I refresh Permalinks or log-out and log-in again.
WordPress 4.2.2
BuddyPress 2.2.3.1
bbPress 2.5.7 (though, the issue continues even when bbPress is deactivated)