If the layout / type is too big you hardly see anything what’s going on on a normal sized monitor (1280×800 or x1024) without scrolling. On the other hand you’ll never fit everything on a small or big screen anyway. So the layout has to be compact on one side – but also prioritize the widgets / elements.
I suggest deflating your design a bit, resizing some sections. It doesn’t need to be as tight (in my opionion too tight) as my design mentioned above – but it would help.