BuddyPress.org

t’s about 30 minutes later and an Internal Redirect Error just showed up in my logs with wp-super-cache out, and all but buddypress plugins out. So it doesn’t look like its a plugin.

So, you had all plugins deactivated except BuddyPress?

doncha’s domain mapping plugin

What are you trying to accomplish with this plugin?

Are you running this as a subdomain or subdirectory install?

I’d suggest that you also create a phpinfo file and provide the output of that file to a pastebin that some of us can look at.