BuddyPress.org

OK,

After 5h looking everywhere I found the problem, my .htacess was wrong… (I miss the rewrite rules to files folder)

So, W3 Total cache works “out of the box”.

I use a subdomain as CDN and everything cached on memcache.

Now I will going to try with more 4 buddypress instalations I have on same server and i let all know if any issue.