BuddyPress.org

Check the permissions and more importantly the ownership rights for the stuff in /blogs.dir/1/files/avatars/1

Everything from /wp-content down. Does your apache user have create rights in that dir chain? apache might be ‘nobody’ or ‘apache’ or something else entirely. Depends on your server setup.

Or like nicola suggests you’ve got some other js loading that is conflicting with the cropper.