BuddyPress.org

I’m using it right now, and there are a couple, very weird and very specific issues. If you do either of these actions, your cache will get wiped out:

1) Edit your BP profile
2) Send a PM

Other than that, I haven’t found any issues! You can change your notification settings and you can post to the ‘wire’ without a problem, but those two things kill the whole cache every time.

So far, I have the following set to never cache:
wp-.*.php
index.php
activity
register
profile
groups

I had issues with W3 total cache and the DB caching. So far I’ve not needed it, though.